Santiago E, Paniagua R, López-Moratalla N
Rev Esp Fisiol. 1977 Mar;33(1):47-52.
Bicarbonate stimulation of hepatic mitochondrial ATPase activity decreased in rats subjected to intense physical training and reached minimum values at the end of the third week. The stimulatory effect of bicarbonate on mitochondrial heart ATPase remained unaffected under equal conditions. ATPase stimulation by dinitrophenol and sensitivity to oligomycin, both in mitochondria from rat liver or heart, were not affected by physical training. Results suggest that stimulation by dinitrophenol and bicarbonate might be due to effects on separate sites of the enzyme.
在进行高强度体育训练的大鼠中，碳酸氢盐对肝线粒体ATP酶活性的刺激作用降低，并在第三周结束时达到最小值。在相同条件下，碳酸氢盐对心脏线粒体ATP酶的刺激作用不受影响。二硝基苯酚对大鼠肝脏或心脏线粒体的ATP酶刺激作用以及对寡霉素的敏感性，均不受体育训练的影响。结果表明，二硝基苯酚和碳酸氢盐的刺激作用可能是由于它们对该酶不同位点的影响。
