SOBOREN J, NYC J F
J Bacteriol. 1963 Apr;85(4):881-8. doi: 10.1128/jb.85.4.881-888.1963.
Soboren, Josephine (University of California, Los Angeles) and Joseph F. Nyc. Effects of certain amino acids on anthranilate production in Neurospora crassa. J. Bacteriol. 85:881-888. 1963.-The level of anthranilic acid produced in cultures of a tryptophanless mutant of Neurospora crassa strain C-83 was closely related to the growth response. A good growth response was attained only on supplements which greatly repressed the level of anthranilate accumulated. The improved growth response of strain C-83 to variable levels of tryptophan and to supplements of the amino acids phenylalanine, tyrosine, leucine, and methionine was correlated with a decreased anthranilate production. The inhibitory effect of these supplements on anthranilate production was ascribed to effects on the mechanisms which regulate the formation of anthranilic acid.
索博伦，约瑟芬（加利福尼亚大学洛杉矶分校）和约瑟夫·F·尼西。某些氨基酸对粗糙脉孢菌邻氨基苯甲酸产生的影响。《细菌学杂志》85:881 - 888。1963年。——粗糙脉孢菌C - 83菌株的一个无色氨酸突变体培养物中产生的邻氨基苯甲酸水平与生长反应密切相关。只有在极大抑制邻氨基苯甲酸积累水平的补充物上才能获得良好的生长反应。C - 83菌株对不同水平色氨酸以及对氨基酸苯丙氨酸、酪氨酸、亮氨酸和蛋氨酸补充物的生长反应改善与邻氨基苯甲酸产量降低相关。这些补充物对邻氨基苯甲酸产生的抑制作用归因于对调节邻氨基苯甲酸形成机制的影响。
