Howng S L, Kwan A L
Department of Surgery, Kaohsiung Medical College, Taiwan, Republic of China.
Gaoxiong Yi Xue Ke Xue Za Zhi. 1992 Jun;8(6):312-9.
Eighty-three patients with intracranial meningioma were retrospectively analyzed with regard to age, sex, anatomic location, mode of presentation and surgical outcome. The ages of the patients ranged from 11 to 77 years. Fifty-five (66%) were females and 28 (34%) were males. The peak incidence occurred between 40 and 49 years. The locations of the meningioma were as follows: 42.2% in the convexity, 15.7% in the parasagittal, 12.1% in the tuberculum sellae, 8.4% in the sphenoid ridge, and three cases with multiple lesions. Forty-two percent of our series were found to have hyperostosis of the skull bone. There were 7 cases with cyst formations found through computed tomography (CT). Histological classification showed 48.3% to be of meningothelimatous type, while 18.4% were of psammomatous type. One of the multiple meningiomas showed two different histological types. The degree of perifocal brain edema at CT scan was found to be related to the symptoms, the size of the tumor and seizure attack. Fifty-three out of 54 patients with episodes of seizures were found to have perifocal brain edema, whereas the histological features were less significant. Seventy-one tumors were treated by total resection and 16 tumors by subtotal resection. Follow-up study from 1 to 7 years showed the rate of recurrence in the total resection group to be 11.3%; in the subtotal resection group without radiation 42.9%, and in the subtotal resection group with radiation 66.7%. The over-all recurrence rate was 19.5% in our series.
对83例颅内脑膜瘤患者的年龄、性别、解剖位置、临床表现方式及手术结果进行了回顾性分析。患者年龄范围为11至77岁。55例(66%)为女性,28例(34%)为男性。发病高峰在40至49岁之间。脑膜瘤的位置如下:凸面42.2%,矢状窦旁15.7%,鞍结节12.1%,蝶骨嵴8.4%,3例为多发病变。我们的病例系列中有42%发现有颅骨骨质增生。通过计算机断层扫描(CT)发现7例有囊肿形成。组织学分类显示,48.3%为脑膜内皮型,18.4%为砂粒型。其中1例多发脑膜瘤显示两种不同的组织学类型。CT扫描时发现瘤周脑水肿程度与症状、肿瘤大小及癫痫发作有关。54例有癫痫发作的患者中,53例发现有瘤周脑水肿,而组织学特征的相关性较小。71例肿瘤行全切除,16例肿瘤行次全切除。1至7年的随访研究显示,全切除组的复发率为11.3%;未行放疗的次全切除组为42.9%,行放疗的次全切除组为66.7%。我们这个系列的总体复发率为19.5%。