Mori A, Suzuki H, Ishiyama I
Department of Legal Medicine School of Medicine, Teikyo University.
Nihon Hoigaku Zasshi. 1992 Aug;46(4):266-70.
Three typical cases of acute methamphetamine intoxication are reported. The concentrations of methamphetamine in the blood were 27.2, 6.43 and 0.60 micrograms/ml, respectively. All three victims had been exposed to high temperature in a bathroom or a closed room in summer at the time of death. Macroscopic autopsy revealed hemorrhagic pulmonary edema, and histologically, diffuse contraction-band necrosis was evident in the myocardium in all cases. The absolute structures of six illegally available methamphetamine showed an (S)-configuration with an optical purity of > 99% in enantiomeric excess and four were racemic form.
报告了三例急性甲基苯丙胺中毒的典型病例。血液中甲基苯丙胺的浓度分别为27.2、6.43和0.60微克/毫升。所有三名受害者在死亡时均于夏季在浴室或封闭房间中暴露于高温环境。大体尸检显示出血性肺水肿，组织学检查发现所有病例心肌均有明显的弥漫性收缩带坏死。六种非法可得的甲基苯丙胺的绝对结构显示为（S）构型，对映体过量的光学纯度>99%，四种为外消旋形式。
