Poltera A A, Owor R, Cox J N
Virchows Arch A Pathol Anat Histol. 1977 Apr 6;373(3):249-65. doi: 10.1007/BF00432240.
The pathological features of 14 cases of human African trypanosomiasis (HAT) occurring in Uganda over an 8 year period are described. Three cases were clinically proven and in all 14 cases a chronic meningoencephalitis was found. In 2 cases there was histological evidence of ganglion radiculitis and in one of these chronic choroiditis and peripheral neuritis associated with chronic myositis were present. The cardiac lesions consisted of a chronic pancarditis of varying degree in 8 cases and in 3 a generalized valvulitis was observed. In 2 cases, specially investigated, generalized lesions of the conducting system were noticed. Previous histopathological descriptions of HAT are briefly reviewed. The present findings are compared with some of those recorded in human american trypanosomiasis and experimental African trypanosomiasis.
本文描述了乌干达8年期间发生的14例人类非洲锥虫病（HAT）的病理特征。其中3例经临床证实，14例均发现慢性脑膜脑炎。2例有神经节神经根炎的组织学证据，其中1例伴有慢性脉络膜炎和与慢性肌炎相关的周围神经炎。心脏病变包括8例不同程度的慢性全心炎，3例观察到全身性瓣膜炎。在2例专门研究的病例中，发现传导系统有广泛性病变。本文简要回顾了以往HAT的组织病理学描述，并将目前的发现与美洲锥虫病和实验性非洲锥虫病的部分记录结果进行了比较。
