Reinhard T, Sundmacher R
Augenklinik, Heinrich-Heine-Universität Düsseldorf.
Klin Monbl Augenheilkd. 1992 Sep;201(3):159-63. doi: 10.1055/s-2008-1045885.
Endogenous eczema represents a considerable risk for perforating keratoplasty because of the associated chronic surface disorders and complex immunological disturbances. Between December 1986 through October 1991 we performed 24 perforating keratoplasties in 20 eyes of 18 patients with endogenous eczema suffering from keratokonus, atopic keratokonjunctivitis and bullous keratopathy after intracapsular cataract extraction. During the follow-up period of 16 (3-48) months 6 transplants failed mostly due to surface problems as well as immune reactions and bacterial transplant infections. Systemically administered ciclosporin A was found to eliminate many of the previously unsolved problems. In summary, 18 out of 20 eyes achieved an improved visual acuity with clear transplants.
内因性湿疹因伴有慢性表面疾病和复杂的免疫紊乱，对穿透性角膜移植术构成相当大的风险。1986年12月至1991年10月期间，我们对18例患有内因性湿疹的患者的20只眼睛进行了24次穿透性角膜移植术，这些患者分别患有圆锥角膜、特应性角结膜炎以及囊内白内障摘除术后的大疱性角膜病变。在16（3 - 48）个月的随访期内，6次移植失败，主要原因是表面问题、免疫反应和细菌性移植感染。发现全身应用环孢素A消除了许多以前未解决的问题。总之，20只眼中有18只眼的移植片清晰，视力得到改善。
