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化学诱导猫的癫痫样发作

CHEMICALLY INDUCED EPILEPTIFORM SEIZURES IN THE CAT.

作者信息

GROSSMAN S P

出版信息

Science. 1963 Oct 18;142(3590):409-11. doi: 10.1126/science.142.3590.409.

Abstract

Long-term epileptiform seizures were induced in the cat by a single stimulation of the basolateral components of the amygdala with cholinergic agents. These electro-physiological changes were accompanied by persisting alterations of the animal's "emotional responsiveness." It is evident dent that electroencephalographic seizure activity and overt behavior can be dissociated in this species.

摘要

通过用胆碱能药物单次刺激杏仁核的基底外侧部分,在猫身上诱发了长期癫痫样发作。这些电生理变化伴随着动物“情绪反应性”的持续改变。显然,在这个物种中,脑电图癫痫活动和明显行为可以分离。

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