Seki M, Nakagawa K, Tsuchiya S, Matsubara T, Kinoshita I, Weng S Y, Tsuchiya E
Department of Chest Surgery, Cancer Institute, Tokyo, Japan.
J Thorac Cardiovasc Surg. 1992 Oct;104(4):876-81.
Between 1959 and 1986, 32 patients with pulmonary metastatic tumors from squamous cell carcinoma of the uterine cervix underwent pulmonary resection. The method of pulmonary resection was correlated with the pathology of the metastases. In 20 patients with pulmonary metastatic lesions 3 cm in diameter or larger, secondary lymph node involvement was observed in 65% and microscopic satellite lesions around the main metastatic lesion were seen in 50%. On the other hand, in none of 12 patients having metastatic lesions smaller than 3 cm was there accompanying lymph node involvement, and microscopic satellite lesions were observed in only one patient among them. Consequently, we concluded that wedge resection with a disease-free margin of 2 cm or a little more from the tumor edge was appropriate for lesions smaller than 3 cm in diameter, and lobectomy with lymph node dissection was necessary for lesions 3 cm in diameter or more.
1959年至1986年间，32例子宫颈鳞状细胞癌肺转移瘤患者接受了肺切除术。肺切除方法与转移灶的病理情况相关。在20例直径3 cm及以上的肺转移病灶患者中，65%观察到继发性淋巴结受累，50%在主要转移病灶周围可见微小卫星病灶。另一方面，在12例转移病灶小于3 cm的患者中，均无伴随淋巴结受累情况，其中仅1例观察到微小卫星病灶。因此，我们得出结论，对于直径小于3 cm的病灶，距肿瘤边缘2 cm或略多的无瘤切缘楔形切除术是合适的，而对于直径3 cm及以上的病灶，则需要行肺叶切除加淋巴结清扫术。
