Anile Marco, Mantovani Sara, Pecoraro Ylenia, Carillo Carolina, Gherzi Lorenzo, Pagini Andreina, Rendina Erino Angelo, Venuta Federico, Diso Daniele
University of Rome Sapienza, Policlinico Umberto I Viale del Policlinico, Rome, Italy.
J Thorac Dis. 2017 Oct;9(Suppl 12):S1273-S1277. doi: 10.21037/jtd.2017.07.46.
This retrospective study is designed to evaluate factors affecting survival in a population of patients receiving pulmonary metastasectomy after gynecologic cancers.
Nineteen patients with isolated lung metastases (one or two) were surgically treated with R0 resection. Four of them underwent lobectomies.
Six patients (31.6%) received adjuvant therapy and 11 (58%) experienced recurrences after metastasectomy. Five- and ten-year survival were 40.9% and 31.4%, respectively. Five-year survival in patients receiving adjuvant therapy was 52.4%. At multivariate analysis factors negatively influencing survival were a disease-free interval (DFI) of less than 24 months and recurrence after pulmonary metastasectomy.
Pulmonary resection for metastatic gynecologic cancer is feasible and effective; adequate selection of patients is mandatory to achieve satisfactory results and long-term survival.
本回顾性研究旨在评估影响妇科癌症患者接受肺转移瘤切除术后生存的因素。
19例孤立性肺转移瘤（1个或2个）患者接受了R0切除手术治疗。其中4例接受了肺叶切除术。
6例患者（31.6%）接受了辅助治疗，11例（58%）在转移瘤切除术后出现复发。5年和10年生存率分别为40.9%和31.4%。接受辅助治疗的患者5年生存率为52.4%。多因素分析显示，对生存有负面影响的因素是无病间期（DFI）小于24个月和肺转移瘤切除术后复发。
妇科癌症肺转移瘤切除术可行且有效；必须适当选择患者以取得满意结果和长期生存。
