WORMSLEY K G
Gut. 1963 Sep;4(3):261-72. doi: 10.1136/gut.4.3.261.
This paper discusses the type of results given by a group of test procedures used in the study of small intestinal dysfunction. While the chemical estimation of faecal fat remains the most valuable criterion for the laboratory detection of malabsorption, the occurrence of abnormal faecal or blood radioactivity also denotes the presence of malabsorption, although some patients with staetorrhoea appear to ;absorb' labelled triolein normally. Analysis of data from the other tests shows that steatorrhoea is not necessarily present in patients who give abnormal results and that the presence of malabsorption does not preclude a normal capacity for handling the test substances. These reservations impair the value of the vitamin A and xylose ;tolerance' tests and serum carotene levels as screening procedures for the determination of malabsorption states. On the other hand, these tests show patterns of results which are useful in differentiating idiopathic from secondary steatorrhoea, since patients with secondary malabsorption often handle one or more of these test substances normally.
本文讨论了一组用于小肠功能障碍研究的测试程序所给出的结果类型。虽然粪便脂肪的化学测定仍然是实验室检测吸收不良最有价值的标准,但粪便或血液放射性异常的出现也表明存在吸收不良,尽管一些腹泻患者似乎能正常“吸收”标记的三油酸甘油酯。对其他测试数据的分析表明,结果异常的患者不一定存在脂肪泻,而且存在吸收不良并不排除处理测试物质的能力正常。这些限制削弱了维生素A和木糖“耐受性”测试以及血清胡萝卜素水平作为确定吸收不良状态筛查程序的价值。另一方面,这些测试显示出的结果模式有助于区分特发性脂肪泻和继发性脂肪泻,因为继发性吸收不良的患者通常能正常处理一种或多种这些测试物质。