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胰腺替代疗法治疗胰腺性脂肪泻

PANCREATIC REPLACEMENT THERAPY IN THE TREATMENT OF PANCREATIC STEATORRHOEA.

作者信息

MARKS I N, BANK S, AIRTH E M

出版信息

Gut. 1963 Sep;4(3):217-22. doi: 10.1136/gut.4.3.217.

DOI:10.1136/gut.4.3.217
PMID:14058262
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1413448/
Abstract

The effect of a whole pancreas preparation (Viokase) has been investigated in 11 patients with pancreatic steatorrhoea and in five patients with steatorrhoea due to other causes. The appearance of the stool, faecal fat, and stool and blood radioactivity after a given dose of I(131) triolein (Raolein) were employed in assessing the response to Viokase therapy. Pancreatic steatorrhoea was considerably improved in the majority of patients, and showed some improvement in the remainder. Viokase appeared to be of limited value in the treatment of post-gastrectomy steatorrhoea, and failed to influence fat absorption in steatorrhoea due to disorder of the small intestine.

摘要

对11例胰腺性脂肪泻患者和5例其他原因所致脂肪泻患者,研究了全胰制剂(胰酶片)的疗效。通过给予一定剂量的碘(131)三油酸甘油酯(放射性油酸甘油酯)后粪便的外观、粪便脂肪以及粪便和血液的放射性,来评估对胰酶片治疗的反应。大多数胰腺性脂肪泻患者病情有显著改善,其余患者也有一定改善。胰酶片对胃切除术后脂肪泻的治疗价值似乎有限,对小肠疾病所致脂肪泻的脂肪吸收没有影响。

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PANCREATIC REPLACEMENT THERAPY IN THE TREATMENT OF PANCREATIC STEATORRHOEA.胰腺替代疗法治疗胰腺性脂肪泻
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Incidence and severity of nutritional deficiency states in chronic exocrine pancreatic insufficency: comparison with nontropical sprue.慢性外分泌性胰腺功能不全时营养缺乏状态的发生率及严重程度:与非热带性口炎性腹泻的比较
Am J Dig Dis. 1966 Aug;11(8):594-606. doi: 10.1007/BF02233507.
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本文引用的文献

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Metabolism in surgical patients. III. Effect of drugs and dietary procedures on fat and nitrogen metabolism in totally gastrectomized patients.外科患者的新陈代谢。III. 药物和饮食措施对全胃切除患者脂肪和氮代谢的影响。
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