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年轻运动女性的应力性骨折:未被怀疑的皮质醇诱导骨质疏松症病例报告

Stress fractures in young athletic women: case reports of unsuspected cortisol-induced osteoporosis.

作者信息

Licata A A

机构信息

Department of Endocrinology, Cleveland Clinic Foundation, OH 44195.

出版信息

Med Sci Sports Exerc. 1992 Sep;24(9):955-7.

PMID:1406194
Abstract

Stress fractures in the female athlete are common events, usually occurring in the lower limb and less often in the pelvic girdle. Two cases are presented of young women athletes who presented with initial lower limb stress fractures, but subsequently fractures of the pelvis and hip thought to be associated with their athletic activity. After careful medical evaluation, they were diagnosed with Cushing's syndrome. One patient had a microadenoma of the pituitary gland secreting excessive amounts of ACTH, and the other had a benign adenoma of the left adrenal gland. Both women had significant decreases in their spinal mineral density. After treatment, partial reversal of these spinal losses occurred. Although stress fractures in the female athlete might be common and thought to be associated with problems of amenorrhea, presentation of unusual anatomical sites for these fractures necessitates a more thorough evaluation for correctable secondary causes.

摘要

女性运动员应力性骨折是常见事件,通常发生在下肢,较少发生在骨盆带。本文介绍了两例年轻女性运动员,她们最初表现为下肢应力性骨折,但随后出现了被认为与其运动活动相关的骨盆和髋部骨折。经过仔细的医学评估,她们被诊断为库欣综合征。一名患者患有垂体微腺瘤,分泌过量促肾上腺皮质激素(ACTH),另一名患者患有左肾上腺良性腺瘤。两名女性的脊柱骨密度均显著降低。治疗后,这些脊柱骨量流失出现了部分逆转。尽管女性运动员应力性骨折可能很常见,且被认为与闭经问题有关,但这些骨折出现在不寻常的解剖部位时,需要进行更全面的评估以寻找可纠正的继发原因。

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Stress fractures in young athletic women: case reports of unsuspected cortisol-induced osteoporosis.年轻运动女性的应力性骨折:未被怀疑的皮质醇诱导骨质疏松症病例报告
Med Sci Sports Exerc. 1992 Sep;24(9):955-7.
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Lower extremity insufficiency fractures: an underappreciated manifestation of endogenous Cushing's syndrome.下肢应力性骨折:内源性库欣综合征的一种未被充分认识的表现。
Osteoporos Int. 2016 Dec;27(12):3645-3649. doi: 10.1007/s00198-016-3712-6. Epub 2016 Aug 15.
3
Bilateral foot pain in a collegiate distance runner.一名大学生长跑运动员的双脚疼痛。
J Athl Train. 1996 Jan;31(1):61-4.
4
Pelvic stress injuries in the athlete: management and prevention.运动员的骨盆应力性损伤:管理与预防
Sports Med. 2003;33(13):1003-12. doi: 10.2165/00007256-200333130-00005.
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Multiple stress fractures. An unusual presentation of Cushing's disease.多发性应力性骨折。库欣病的一种不寻常表现。
West J Med. 1995 Apr;162(4):364-6.