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聚二氧六环酮(PDS)缝线的显微外科应用:一项实验报告。

Microsurgical use of polydioxanone (PDS) suture: an experimental report.

作者信息

Takeishi M, Hirase Y, Kojima T

机构信息

Department of Plastic and Reconstructive Surgery, Jikei University School of Medicine, Tokyo, Japan.

出版信息

Microsurgery. 1992;13(5):268-72. doi: 10.1002/micr.1920130515.

DOI:10.1002/micr.1920130515
PMID:1406232
Abstract

Although many technological advances have been made in surgical materials, nylon is still the main suture material use for microvascular surgery. This study sought to evaluate polydioxanone (PDS) sutures for use in microvascular anastomoses. Twenty-eight male Sprague-Dawley rats were used in this experiment. Spatula-type needles with 9-0 PDS suture were used to anastomose the right femoral arteries, with 9-0 nylon used on the left side. The arteries were observed for 1, 2, 3, 4, 8, 12, and 16 weeks after surgery to determine arterial patency and to evaluate vascular pathology. Results were comparable between PDS and nylon. We suggest that if the suture material is redesigned to allow smooth passage through the tissue, and if the needle used in conjunction with the suture is improved, PDS may offer an excellent material for microvascular anastomosis.

摘要

尽管手术材料已经取得了许多技术进步,但尼龙仍然是微血管手术中使用的主要缝合材料。本研究旨在评估聚二氧六环酮(PDS)缝线在微血管吻合术中的应用。本实验使用了28只雄性斯普拉格-道利大鼠。用带有9-0 PDS缝线的刮刀型针吻合右侧股动脉,左侧使用9-0尼龙线。术后1、2、3、4、8、12和16周观察动脉通畅情况并评估血管病理学变化。PDS和尼龙的结果相当。我们认为,如果重新设计缝合材料以使其能顺利穿过组织,并且改进与缝线配合使用的针,PDS可能会成为微血管吻合的优质材料。

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