Huang G K, Li H Q, Wu X M
Department of Orthopaedic Surgery, Shanghai First People's Hospital, PROC.
Microsurgery. 1995;16(7):505-9. doi: 10.1002/micr.1920160713.
A synthetic, monofilament, slowly absorbing suture material, polyglyconate suture was tested to determine its suitability for use in microarterial anastomoses under ordinary tension and under undue tension. Microvascular repair of 34 rat femoral arteries averaging 0.63 mm in diameter using 8-0 polyglyconate suture on an atraumatic needle gave an immediate patency rate of 100% and a late patency rate of 94.1% after 1 to 24 weeks. Microanastomoses of 30 rabbit femoral arteries averaging 1.43 mm in diameter using 8-0 polyglyconate suture on an atraumatic needle gave an immediate patency rate of 100% and a late patency rate of 96.7% when a vessel segment of 3 to 7 mm was resected. Morphological studies included light microscopy and scanning electron microscopy. The results showed that polyglyconate suture retains tensile strength for an adequate period to allow vascular healing and causes a less pronounced tissue response than nonabsorbable nylon suture. Complete absorption of the suture material was followed by a complete regeneration of the vessel wall. These results demonstrated that absorbable polyglyconate suture might be suitable for microvascular anastomosis of arteries under ordinary tension and under tension to a certain degree.
聚乙醇酸缝线是一种合成的单丝、缓慢吸收的缝合材料，对其在正常张力和过度张力下用于显微动脉吻合的适用性进行了测试。使用8-0聚乙醇酸缝线和无损伤针，对34只大鼠平均直径为0.63mm的股动脉进行微血管修复，术后即刻通畅率为100%，1至24周后的后期通畅率为94.1%。使用8-0聚乙醇酸缝线和无损伤针，对30只平均直径为1.43mm的兔股动脉进行显微吻合，切除3至7mm的血管段后，术后即刻通畅率为100%，后期通畅率为96.7%。形态学研究包括光学显微镜和扫描电子显微镜检查。结果表明，聚乙醇酸缝线能在足够长的时间内保持抗张强度，以利于血管愈合，且与不可吸收的尼龙缝线相比，引起的组织反应不那么明显。缝线材料完全吸收后，血管壁完全再生。这些结果表明，可吸收的聚乙醇酸缝线可能适用于正常张力和一定程度张力下的动脉微血管吻合。
