CAHN C H
Can Med Assoc J. 1963 Oct 5;89(14):719-20.
Chlorprothixene, a thioxanthine derivative, claimed to have broad-spectrum antipsychotic properties, was compared with phenothiazine derivatives in the setting of a psychiatric admission service and aftercare clinic.In 32 female patients with paranoid symptoms, chlorprothixene in high dosage ranges (200 to 1200 mg. daily) was found to be as effective as similar doses of chlorpromazine in controlling the symptoms; fewer side effects were noted.
氯丙硫蒽是一种硫杂蒽衍生物,据称具有广谱抗精神病特性。在一家精神病住院部和后续护理诊所中,将其与吩噻嗪衍生物进行了比较。在32名有偏执症状的女性患者中,发现高剂量范围(每日200至1200毫克)的氯丙硫蒽在控制症状方面与相似剂量的氯丙嗪一样有效;且副作用较少。