HINEGARDNER R T, ENGELBERG J
Science. 1963 Nov 22;142(3595):1083-5. doi: 10.1126/science.142.3595.1083.
A mutation in the genetic code would place new amino acids in certain loci and entirely eliminate amino acids from other loci of practically all proteins in an organism. It is reasonable to postulate that mutations of this kind cannot supplant the original code. The genetic code, once established, would therefore remain invariant.
遗传密码中的突变会在某些位点引入新的氨基酸，并几乎从生物体中所有蛋白质的其他位点完全去除氨基酸。据推测，这类突变无法取代原始密码，这是合理的。因此，一旦确立，遗传密码将保持不变。
