Sekiya T, Manabe H, Iwabuchi T, Narita T
Department of Neurosurgery, Hirosaki University School of Medicine.
No Shinkei Geka. 1992 Oct;20(10):1063-8.
The dura mater adjacent to the attachment of meningiomas was enhanced on MR imaging with intravenous Gd-DTPA infusion. It was examined histologically in four patients with intracranial globoid meningiomas. Histological examination revealed that there was no tumor cell invasion within the dura mater enhanced on MR imaging, except at the point of their attachment. A layer of tumor cells was occasionally observed on the surface of the dura mater, but this was limited to within 5 mm of the tumor margin. Our electronmicroscopic observation indicated that enhancement of the dura mater adjacent to the attachment of meningiomas was caused by increased vascular permeability of the dural vessels and extended extravascular space.
静脉注射钆喷酸葡胺（Gd-DTPA）后，磁共振成像（MR）显示，与脑膜瘤附着处相邻的硬脑膜有强化表现。对4例颅内球状脑膜瘤患者进行了组织学检查。组织学检查发现，在MR成像上强化的硬脑膜内，除了脑膜瘤的附着点外，没有肿瘤细胞浸润。偶尔在硬脑膜表面观察到一层肿瘤细胞，但这仅限于肿瘤边缘5毫米范围内。我们的电子显微镜观察表明，与脑膜瘤附着处相邻的硬脑膜强化是由硬脑膜血管通透性增加和血管外间隙扩大所致。
