Aragon C M, Amit Z
Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, Quebec, Canada.
Neuropharmacology. 1992 Jul;31(7):709-12. doi: 10.1016/0028-3908(92)90150-n.
The effects of the catalase inhibitor, 3-amino-1,2,4-triazole (AT), on maintenance of voluntary consumption of ethanol was tested in male Long-Evans rats. AT produced a dose-dependent reduction in ethanol intake but did not affect total fluid consumption. AT also produced a dose-dependent inhibition of brain catalase lasting throughout the drinking period. These results suggest a role for brain catalase in determining the level of ethanol intake in rats.
