Rajasuo A, Meurman J H, Murtomaa H, Torkko H
Valkeala Military Hospital, Finnish Defence Forces.
Oral Surg Oral Med Oral Pathol. 1992 Oct;74(4):431-6. doi: 10.1016/0030-4220(92)90288-2.
This study was made to investigate the effect of extraction of third molars on subgingival microbes in 39 generally and gingivally healthy men with an average age of 20.2 years (SD 0.9). Microbial samples were taken from the pericoronal space of symptom-free partly erupted lower third molars and from the adjacent gingival pockets of the second molars. The samples were cultivated anaerobically. All partly erupted third molars were extracted from 20 subjects. A control group of 19 subjects was left untreated. Microbe sampling was repeated 2 and 5 months postoperatively with highly significant results. It was shown that at baseline the number of black-pigmented gram-negative bacteria and Fusobacterium species was more frequent in third molar than in second molar sites. The total bacterial count decreased significantly at the second molar sites after extraction of the third molars when compared with the control group. Before the extractions, black-pigmented gram-negative bacteria were detected in 45% of the test subjects and Actinobacillus actinomycetemcomitans in 20%. The respective postoperative figures were 30% for black-pigmented gram-negative bacteria and 10% for Actinobacillus actinomycetemcomitans. Capnocytophaga species were not affected by the extractions. The findings suggest that erupting third molars may harbor harmful bacteria that can be reduced by eradicating the foci.
本研究旨在调查拔除第三磨牙对39名一般健康且牙龈健康的男性（平均年龄20.2岁，标准差0.9）龈下微生物的影响。微生物样本取自无症状的部分萌出的下颌第三磨牙的冠周间隙以及第二磨牙相邻的龈袋。样本进行厌氧培养。从20名受试者中拔除所有部分萌出的第三磨牙。19名受试者组成的对照组未接受治疗。术后2个月和5个月重复进行微生物采样，结果非常显著。结果显示，在基线时，黑色色素革兰氏阴性菌和梭杆菌属在第三磨牙部位比在第二磨牙部位更为常见。与对照组相比，拔除第三磨牙后，第二磨牙部位的细菌总数显著减少。拔牙前，45%的受试对象检测到黑色色素革兰氏阴性菌，20%检测到伴放线放线杆菌。术后相应数字分别为黑色色素革兰氏阴性菌30%，伴放线放线杆菌10%。二氧化碳嗜纤维菌属不受拔牙影响。研究结果表明，正在萌出的第三磨牙可能携带有害细菌，通过根除病灶可以减少这些细菌。
