Barzó P, Pávics L, Borda L, Bodosi M, Dóczi T, Katona E
Szent-Györgyi Albert Orvostudományi Egyetem, Szeged.
Orv Hetil. 1992 Sep 13;133(37):2347-50, 2355.
The aim of this study was the development of a simple bedside test to assess cerebrovascular reserve capacity using transcranial Doppler sonography. We tried to validate the increase in blood flow velocity as cerebrovascular reserve capacity in 20 (3 normal, 7 TIA, 10 completed stroke) patients. They were studied using transcranial Doppler sonography and rCBF SPECT before and after injection of 1 g acetazolamide. Their increases in blood flow velocity and changes in cerebral blood flow correlated significantly in the symptomatic hemispheres (p less than 0.001). Blood flow velocity between the two hemispheres (symptomatic and asymptomatic) was not significantly different at rest. We offer these simple and reliable methods in clinical studies to clarify the frequency of ischemic stroke of hemodynamic origin.
本研究的目的是开发一种简单的床旁试验，利用经颅多普勒超声评估脑血管储备能力。我们试图在20例患者（3例正常、7例短暂性脑缺血发作、10例完全性卒中）中验证血流速度的增加作为脑血管储备能力。在注射1g乙酰唑胺前后，使用经颅多普勒超声和rCBF SPECT对他们进行研究。在有症状的半球中，他们的血流速度增加与脑血流量变化显著相关（p<0.001）。两个半球（有症状和无症状）之间的血流速度在静息时无显著差异。我们在临床研究中提供这些简单可靠的方法，以阐明血流动力学起源的缺血性卒中的发生率。
