Corradi G, Molnár G, Pánovics J, Lindeisz F
Urológiai Klinika, Semmelweis Orvostudományi Egyetem, Budapest.
Orv Hetil. 1992 Oct 25;133(43):2759-62, 2765-6.
The data concerning bacteriospermia--are very different in the literature. Asymptomatic andrologic patients, and as control group--patients of the outpatient department for male adnexitis--were studied. Cultivation of aerobic bacteria and mycoplasmas has been recently accomplished by quantitative bacteriological analysis and chlamydia diagnostic. The microbiological screening of 210 andrologic patients ejaculate has given the following results: 19.6% were sterile, 21.0% were colonised by apathogens, 59.1% were positive: 6.2% Mycoplasma hominis, 15.8% Ureaplasma urealyticum, 13.3% Chlamydia trachomatis, 51.9% other aerobic pathogens. 27.6% of samples contained more then one kind of bacteria strains. Quantitative isolation of aerobics and mycoplasmas in both andrological and male adnexitis patients groups showed the following distribution. In the andrologic groups 14.7% of samples contained 10(4) CFU/ml, 9.6% more than 10(4) CFU/ml aerobic bacteria; in the male adnexitis group nearly twice higher values could be observed (20.2% and 19.5%). The distribution of mycoplasma CFU/ml was the following; andrologie group: 20.1% of samples contained 10(4) mycoplasma CFU/ml, 37.5% more than 10(4) CFU/ml; in the male adnixitis group the identical values: 22.9%, 66.9%. Chi 2 statistical analysis showed significant difference ((p = 0.000) in the distribution of data in the two groups. On the other hand both of the groups contained all kinds of bacteriological concentration and even negative cases. Therefore authors suggest more biochemical investigations for detecting inflammatory diseases. Spermaparameters (motility and progressive motility) of andrological patients, divided by sperm concentration (cell number above and under 20 million/ml) and the degree of infection (non infected, slightly infected, and above 10(4) CFU/ml) were significantly different in the seriously infected group by variance analysis (p = 0.000).
关于精液细菌感染的数据——文献中的记载差异很大。对无症状的男科患者以及作为对照组的男性附属腺炎门诊患者进行了研究。近期通过定量细菌学分析和衣原体诊断完成了需氧菌和支原体的培养。对210例男科患者的精液进行微生物筛查，结果如下：19.6%无菌，21.0%被非致病性细菌定植，59.1%呈阳性：人型支原体占6.2%，解脲脲原体占15.8%，沙眼衣原体占13.3%，其他需氧病原体占51.9%。27.6%的样本含有不止一种菌株。对男科患者组和男性附属腺炎患者组需氧菌和支原体的定量分离显示出以下分布情况。在男科患者组中，14.7%的样本含有10⁴CFU/ml的细菌，9.6%含有超过10⁴CFU/ml的需氧菌；在男性附属腺炎组中，可观察到的数值几乎高出一倍（分别为20.2%和19.5%）。支原体CFU/ml的分布情况如下：男科患者组：20.1%的样本含有10⁴支原体CFU/ml，37.5%含有超过10⁴CFU/ml；在男性附属腺炎组中，相同的数值分别为22.9%和66.9%。卡方统计分析显示两组数据分布存在显著差异（p = 0.000）。另一方面，两组都包含了各种细菌浓度情况，甚至还有阴性病例。因此，作者建议进行更多的生化检查以检测炎症性疾病。通过方差分析，男科患者的精子参数（活力和前向运动能力），按照精子浓度（每毫升细胞数高于和低于2000万）以及感染程度（未感染、轻度感染和高于10⁴CFU/ml）划分，在严重感染组中存在显著差异（p = 0.000）。
