EDWARDS F C, TRUELOVE S C
Gut. 1963 Dec;4(4):299-315. doi: 10.1136/gut.4.4.299.
The authors have produced a unique study of 624 patients with ulcerative colitis for they have achieved a 100% follow-up of all these patients admitted to the Radcliffe Infirmary or to the Churchill Hospital, Oxford, from 1938 to March 1962 inclusive or who attended as out-patients during the same period. They are therefore able to present a most important analysis of the natural history of ulcerative colitis as it occurs in the general population. Part I concerns the short-term prognosis in the initial attack, Part II the long-term prognosis; Part III discusses the complications of the disease, and Part IV the risk of carcinoma.
作者们对624例溃疡性结肠炎患者进行了一项独特的研究，因为他们对1938年至1962年3月（含）期间入住拉德克利夫医院或牛津丘吉尔医院的所有这些患者，以及同期作为门诊患者就诊的患者进行了100%的随访。因此，他们能够对溃疡性结肠炎在普通人群中的自然史进行一项极其重要的分析。第一部分涉及初次发作的短期预后，第二部分涉及长期预后；第三部分讨论该疾病的并发症，第四部分讨论癌变风险。
