豚鼠7S抗体的特性。V. 豚鼠γ-2抗体对γ-2抗体引发的被动免疫溶解的抑制作用
PROPERTIES OF GUINEA PIG 7S ANTIBODIES. V. INHIBITION BY GUINEA PIG GAMMA-2 ANTIBODIES OF PASSIVE IMMUNE LYSIS PROVOKED BY GAMMA-2 ANTIBODIES.
作者信息
KOURILSKY F M, BLOCH K J, BENACERRAF B, OVARY Z
出版信息
J Exp Med. 1963 Nov 1;118(5):699-709. doi: 10.1084/jem.118.5.699.
Abstract
Passive immune lysis of antigen-coated erythrocytes provoked in vitro by guinea pig gamma(2) antihapten antibodies in the presence of complement, is inhibited by guinea pig gamma(1) antibodies directed against the same specificity. This inhibition of the lytic effect of complement-fixing gamma(2) antibodies is presumably due to the competition for antigen by non-lytic gamma(1) antibodies.
摘要
在补体存在的情况下，豚鼠γ(2)抗半抗原抗体在体外引发的抗原包被红细胞的被动免疫溶解，会受到针对相同特异性的豚鼠γ(1)抗体的抑制。补体结合γ(2)抗体的溶解作用受到抑制，推测是由于非溶解γ(1)抗体与抗原发生了竞争。
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