Meguid M M, Yang Z J, Ratto C, Meguid R A, Hitch D C, Kubota A, Campos A C
Department of Surgery, University Hospital, SUNY Health Science Center, Syracuse 13210.
Physiol Behav. 1992 Sep;52(3):597-601. doi: 10.1016/0031-9384(92)90353-4.
The influence of general anesthesia and operation on dynamics of postoperative food intake resumption was investigated in eight rats. A laparotomy was performed on each rat under anesthesia induced by intraperitoneally injected chloral hydrate. Spontaneous food intake and feeding indexes were continuously measured using an Automated Computerized Rat Eater Meter (ACREM) before and after operation. Although spontaneous food intake and all feeding indexes were depressed immediately following anesthesia and operation, each feeding index was depressed to a greater degree during the dark vs. the light cycle. Initially, rats fully capable of eating ate fewer, smaller, and shorter meals. The return to normal of each feeding index differed temporally. Thus, although meal number normalized by the third postoperative day, meal size by the sixth postoperative day, and meal duration by the fourth postoperative day, normalization of meal number during the light cycle occurred sooner than during the dark cycle, while the converse occurred with meal size and meal duration.
在八只大鼠中研究了全身麻醉和手术对术后食物摄入恢复动态的影响。在腹腔注射水合氯醛诱导的麻醉下，对每只大鼠进行剖腹手术。使用自动计算机化大鼠进食量计（ACREM）在手术前后连续测量自发食物摄入量和进食指数。尽管麻醉和手术后自发食物摄入量和所有进食指数立即下降，但在黑暗周期与光照周期相比，每个进食指数下降的程度更大。最初，完全有进食能力的大鼠吃得更少、更小且进食时间更短。每个进食指数恢复正常的时间不同。因此，尽管进食次数在术后第三天恢复正常，进食量在术后第六天恢复正常，进食持续时间在术后第四天恢复正常，但光照周期中进食次数的恢复比黑暗周期更快，而进食量和进食持续时间的情况则相反。
