Meguid M M, Gleason J R, Yang Z J
Department of Surgery, University Hospital, SUNY Health Science Center, Syracuse 13210.
Physiol Behav. 1993 Sep;54(3):471-5. doi: 10.1016/0031-9384(93)90238-b.
The role of olfactory input in the regulation of food intake and feeding patterns in rats was investigated by performing bilateral olfactory bulbectomy. Compared to control rats, bulbectomized rats ate the same amounts of food, but did so via a decrease in meal size, and a doubling in meal number. Although no increase in meal duration occurred, the exploratory behavior of sniffing during meals and between meals also increased significantly. While it is not yet clear how the olfactory bulbs participate in regulating food intake configuration resulting in changed feeding patterns, their clinical role can be appreciated by observing the acute changes in feeding pattern that occur when their input to the lateral hypothalamic area is damaged experimentally.
通过进行双侧嗅球切除术，研究了嗅觉输入在调节大鼠食物摄入量和进食模式中的作用。与对照大鼠相比，嗅球切除的大鼠进食量相同，但进食量通过每餐食量的减少和进餐次数的加倍来实现。虽然进餐持续时间没有增加，但进餐期间和两餐之间的嗅探探索行为也显著增加。虽然尚不清楚嗅球如何参与调节导致进食模式改变的食物摄入结构，但通过观察实验性损伤其向外侧下丘脑区域的输入时发生的进食模式急性变化，可以认识到它们的临床作用。
