DAVENPORT H T, BARR M N
Can Med Assoc J. 1963 Dec 28;89(26):1309-13.
The gravimetric method of measuring blood loss was used during all types of pediatric operations at The Montreal Children's Hospital. Results of 1787 such measurements indicated that the method is of value in the management of transfusion. Grading blood loss as minor, moderate or severe, in terms of its relation to total blood volume or body weight is a procedure of practical value. Operations were grouped into those that usually led to a loss of less than 10% of the blood volume (7.5 ml./kg.), those with a loss usually between 10% and 14% and those with blood loss usually over 14% (10.5 ml./kg.), in order that appropriate plans for transfusion could be made to reduce the incidence of serious hypovolemia without fear of cardiovascular overloading. Blood loss at operation (adenotonsillectomy) was noted to vary considerably among surgeons but was fairly constant for each surgeon and seemed to be independent of the surgeon's experience. Two alleged hemostatic agents, adrenochrome carbazone (Statimo) and estrogenic substances (Premarin), were not effective in reducing the amount of blood lost during adenotonsillectomy. The importance of calculation of approximate equivalent amounts of blood at various ages of childhood is emphasized.
蒙特利尔儿童医院在各类儿科手术中采用重量法测量失血量。1787次此类测量结果表明,该方法在输血管理方面具有价值。根据失血量与总血容量或体重的关系,将失血量分为少量、中等或大量,这是一种具有实用价值的做法。手术被分为几类:一类是通常导致失血量少于血容量10%(7.5毫升/千克)的手术;一类是失血量通常在10%至14%之间的手术;还有一类是失血量通常超过14%(10.5毫升/千克)的手术,以便制定适当的输血计划,降低严重血容量不足的发生率,同时不用担心心血管系统负荷过重。手术(腺样体扁桃体切除术)中的失血量在不同外科医生之间差异很大,但对每位外科医生来说相对稳定,而且似乎与外科医生的经验无关。两种所谓的止血剂,安络血(安特诺新)和雌激素类物质(倍美力),在减少腺样体扁桃体切除术中的失血量方面无效。强调了计算儿童不同年龄段大致等量血液的重要性。