Böttcher-Gandor C, Ullsperger P
Wilhelm-Griesinger-Krankenhaus, Berlin, Germany.
Psychophysiology. 1992 Sep;29(5):546-50. doi: 10.1111/j.1469-8986.1992.tb02028.x.
The mismatch negativity, isolated as a component of the event-related brain potential elicited by deviant auditory stimuli, was suggested by Näätänen (1984) as an indirect measure of the inferred neuronal representation of standard stimuli. The purpose of the present study was to determine the duration of the neuronal representation by varying the interstimulus intervals of 1, 6, and 10 seconds within experimental blocks. Mismatch negativities were found to be elicited by deviant stimuli (1500-Hz tones, sequential probability 10%) following standard stimuli (1000-Hz tones) with interstimulus intervals of 1, 6, and 10 s as well. The results suggest a duration of neuronal representation of at least 10 s. The within-block variation of interstimulus interval, the rather low temporal probability of deviants, and their large frequency deviance might explain the present results contradicting earlier findings that suggested a shorter duration of that neuronal representation.
失匹配负波是由异常听觉刺激诱发的事件相关脑电位的一个成分，Näätänen（1984年）提出将其作为对标准刺激推断的神经元表征的一种间接测量方法。本研究的目的是通过在实验块内改变1秒、6秒和10秒的刺激间隔来确定神经元表征的持续时间。发现失匹配负波也可由标准刺激（1000赫兹纯音）之后的异常刺激（1500赫兹纯音，序列概率10%）诱发，刺激间隔分别为1秒、6秒和10秒。结果表明神经元表征的持续时间至少为10秒。刺激间隔在块内的变化、异常刺激相当低的时间概率以及它们较大的频率偏差，可能解释了本研究结果与早期研究结果相矛盾的原因，早期研究结果表明该神经元表征的持续时间较短。
