Nathwani D, Badial R, Khaund R R, Douglas J G, Smith C C
Infection Unit, City Hospital, Aberdeen.
Scott Med J. 1992 Aug;37(4):106-10. doi: 10.1177/003693309203700404.
All 110 patients seen in North East Scotland after contracting malaria from foreign travel were treated in the Regional Infection Unit in Aberdeen. Those patients managed there from January 1980 to March 1991 are described. There were 54 episodes of Plasmodium falciparum malaria (49%) and 26 episodes (23%) of Plasmodium vivax malaria. The remainder had either mixed infection or were diagnosed as malaria on high clinical probability. The majority of the patients were male (80%) and under 40 years of age (84%). Most patients were either caucasians born in the UK (69%) or native Africans (23%) who were students recently arrived for further education or who had returned from visiting their country of origin for summer holidays. The British residents acquired infection either while on oil related business in West or Central Africa (46%) or after travelling on holiday (30%). The peak incidence of presentation was August and September. 93.5% of patients with falciparum malaria had returned or originated from Africa. 42% with vivax malaria had visited Africa and 27% Papua New Guinea. 70% had been prescribed antimalarial prophylaxis but less than half of these took their medication correctly. The majority of patients with falciparum malaria presented within two weeks of arrival in Britain while patients with vivax malaria presented at varying (but generally longer) intervals, 42% being diagnosed more than three months after exposure. Falciparum infection was more severe although there have been no deaths in the unit from malaria. Our experience seemed of interest and worth reporting because of the number of patients whose infection reflected travel related to the off shore oil industry, which is centred in Aberdeen.
在苏格兰东北部因境外旅行感染疟疾的110名患者均在阿伯丁的地区感染科接受治疗。本文描述了1980年1月至1991年3月在该科室接受治疗的患者情况。其中有54例恶性疟原虫疟疾发作（49%），26例间日疟原虫疟疾发作（23%）。其余患者为混合感染或因高度疑似疟疾而确诊。大多数患者为男性（80%），年龄在40岁以下（84%）。多数患者是出生在英国的白种人（69%）或非洲本地人（23%），这些非洲本地人是近期来英国深造的学生或回国度暑假的人。英国居民感染疟疾要么是在西非或中非从事与石油相关的业务时（46%），要么是在度假旅行后（30%）。就诊的高峰发病率出现在8月和9月。93.5%的恶性疟患者是从非洲返回或来自非洲。42%的间日疟患者去过非洲，27%去过巴布亚新几内亚。70%的患者曾接受抗疟预防用药，但其中不到一半的人正确服药。大多数恶性疟患者在抵达英国后的两周内发病，而间日疟患者发病时间间隔不一（但通常较长），42%的患者在接触后三个月以上才被确诊。尽管该科室没有因疟疾死亡的病例，但恶性疟感染更为严重。由于许多患者的感染与以阿伯丁为中心的近海石油行业相关的旅行有关，我们的经验似乎值得关注和报道。
