Dyson D H, Atilola M
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Canada.
Vet Surg. 1992 Sep-Oct;21(5):418-21. doi: 10.1111/j.1532-950x.1992.tb01720.x.
Oxymorphone (0.2 mg/kg, maximum 4.5 mg) or butorphanol (0.2 mg/kg, maximum 4.5 mg), with acepromazine (0.05 mg/kg) and atropine (0.02 mg/kg), was administered intravenously to 106 healthy dogs undergoing radiographic examination of the pelvis. The dogs were returned to their owners after the examination and opioid reversal with naloxone (0.02 mg/kg intravenously, maximum 0.4 mg). Questionnaires were completed by the radiology staff and owners of the dogs, and results were coded by one person, all of whom were unaware of the treatment used. There was a lower incidence of temporary excitement upon injection and less panting in dogs sedated with butorphanol than with oxymorphone. There were no significant differences in degree of sedation, response to noise or manipulation, vocalization, defecation, heart rate, reversibility, sedation after reversal, or personality. Both forms of chemical restraint were satisfactory for radiographic examination of the pelvis, with no significant side effects in healthy dogs.
将0.2毫克/千克（最大剂量4.5毫克）的羟吗啡酮或0.2毫克/千克（最大剂量4.5毫克）的布托啡诺与乙酰丙嗪（0.05毫克/千克）和阿托品（0.02毫克/千克）静脉注射给106只接受骨盆X光检查的健康犬。检查结束后，给犬静脉注射纳洛酮（0.02毫克/千克，最大剂量0.4毫克）进行阿片类药物逆转，然后将犬归还其主人。放射科工作人员和犬主填写了调查问卷，结果由一人编码，所有人员均不知道所采用的治疗方法。与使用羟吗啡酮镇静的犬相比，使用布托啡诺镇静的犬注射时出现短暂兴奋的发生率较低，气喘也较少。在镇静程度、对噪音或操作的反应、发声、排便、心率、可逆性、逆转后的镇静或性格方面，两者没有显著差异。两种化学保定方法对骨盆X光检查均令人满意，对健康犬没有明显的副作用。
