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[铟-111或锝-99m-六甲基丙烯胺肟标记的粒细胞作为活动性心内膜炎阶段的特异性标志物——30例疑似心内膜炎患者临床、组织学和闪烁显像结果比较]

[Indium-111 or Tc-99m-HMPAO marked granulocytes as specific markers of florid stage endocarditis--results comparing clinical, histological and scintigraphic findings in 30 patients with suspected endocarditis].

作者信息

Borst U, Becker W, Maisch B, Börner W, Kochsiek K

机构信息

Zentrum für Innere Medizin, Universitätsklinik Marburg.

出版信息

Z Kardiol. 1992 Aug;81(8):432-7.

PMID:1413951
Abstract

Thirty patients with clinically suspected infective endocarditis were scanned with Indium-111- or Tc-99m-HM-PAO-labeled granulocytes. The scans were correlated with the clinical course, and in 20 cases with the results from histologic examination of the valves. In six cases the scintigraphic examination gave correct positive results, in three cases false negative, in one case a false positive, and in 20 cases correct negative results. If we limit the analysis to only the histologically proven cases, our data suggest a specificity of the method of 86% and a sensitivity of about 67%.

摘要

对30例临床怀疑患有感染性心内膜炎的患者进行了铟-111或锝-99m-六甲基丙烯胺肟标记的粒细胞扫描。扫描结果与临床病程相关,20例与瓣膜组织学检查结果相关。闪烁扫描检查在6例中给出了正确的阳性结果,3例为假阴性,1例为假阳性,20例为正确的阴性结果。如果我们仅将分析局限于组织学证实的病例,我们的数据表明该方法的特异性为86%,敏感性约为67%。

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