Kato M
Hokkaido Igaku Zasshi. 1977 Jan;52(1):59-62.
In order to investigate the effects of Dantrolene sodium on the nervous system, the experiments were carried out on cats. 1. Group Ia spindle afferent discharges were suppressed in 6 out of 14 cases following application of the drug. The effect lasted for 20 to 90 minutes. 2. No significant effects were observed on spinal mono- and polysynaptic reflexes, nor was seen on interneurons. However, 3 out of 9 Renshaw cells were facilitated and 3 were inhibited after Dantrolene sodium application. 3. Alternating discharges in the ventral root filaments, evoked by stimulation of N. cuneiformis, were suppressed by the drug application.
为了研究丹曲林钠对神经系统的影响，在猫身上进行了实验。1. 给药后，14只猫中有6只的Ia类肌梭传入放电受到抑制。这种作用持续20至90分钟。2. 未观察到对脊髓单突触和多突触反射有显著影响，对中间神经元也无影响。然而，应用丹曲林钠后，9个闰绍细胞中有3个被易化，3个被抑制。3. 刺激楔状神经所诱发的腹根细丝交替放电，在给药后受到抑制。
