健康志愿者垂体形态的磁共振成像评估：年龄和性别相关差异
MR assessment of pituitary gland morphology in healthy volunteers: age- and gender-related differences.
作者信息
Doraiswamy P M, Potts J M, Axelson D A, Husain M M, Lurie S N, Na C, Escalona P R, McDonald W M, Figiel G S, Ellinwood E H
机构信息
Department of Psychiatry, Duke University Medical Center, Durham, NC 27710.
出版信息
AJNR Am J Neuroradiol. 1992 Sep-Oct;13(5):1295-9.
PURPOSE AND METHODS
High-field MR images at 1.5 T were used to characterize the effects of age and gender on pituitary size and shape in a sample of 71 adult volunteers (40 females), aged 21 to 82 years.
FINDINGS
For all subjects, age was inversely correlated with pituitary height (r = -.43, P less than .0002) and cross-sectional area (r = -.35, P less than .0028). Age-specific gender differences were also present in pituitary height and area. A convex upper pituitary margin was more common in females (P = .002) and younger subjects (P = .009).
CONCLUSIONS
This study confirms that aging is accompanied by gender-specific changes in pituitary size and shape, and provides normative data that may facilitate evaluation of the pituitary gland in neuroendocrine disorders.
目的与方法
使用1.5T高场强磁共振成像来描述年龄和性别对71名年龄在21至82岁的成年志愿者（40名女性）样本中垂体大小和形状的影响。
研究结果
对于所有受试者，年龄与垂体高度呈负相关（r = -0.43，P < 0.0002）以及与横截面积呈负相关（r = -0.35，P < 0.0028）。垂体高度和面积也存在特定年龄的性别差异。垂体上缘呈凸形在女性中更常见（P = 0.002）且在年轻受试者中更常见（P = 0.009）。
结论
本研究证实衰老伴随着垂体大小和形状的性别特异性变化，并提供了可能有助于评估神经内分泌疾病中垂体的规范数据。
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