Ülkü Göktuğ, Elbir Çağrı, Abbasoğlu Bilal, Tonge Caghan, Demirtaş Oğuz Kağan, Dolgun Habibullah, Yılmaz Erdal Reşit, Civlan Serkan, Sevmez Fatma, Beger Orhan
Ankara Etlik City Hospital, Department of Neurosurgery, Ankara, Türkiye.
Department of Neurosurgery, Pamukkale University Faculty of Medicine, Denizli, Türkiye.
Surg Radiol Anat. 2025 Apr 16;47(1):120. doi: 10.1007/s00276-025-03632-w.
To analyze the relationship of the height of the pituitary gland (HPG) with the heights of the dorsum sellae (HDS) and tuberculum sellae (HTS) on pediatric magnetic resonance imaging (MRI) views.
MRI slices of 180 healthy children (100 males and 80 females) aged 1-18 years were included in the study.
Average HPG, HTS and HDS values were determined as 6.66 ± 1.58 mm, 10.97 ± 1.99 mm, 13.62 ± 2.67 mm, respectively. No statistically significant difference was determined between the measurements in term of sex. All parameters correlated with pediatric ages. HPG increased up to the prepubescent period, and decreased after this period (p < 0.001). HDS and HTS increased with an irregular pattern (p < 0.001). There were six children (3.33%) with HPG > 10 mm. There was no child with HPG/HDS > 1 or HPG/HTS > 1.
This work provided three substantial additions to the literature as follows: (a) all pediatric HPGs were distinctly smaller than HDSs and HTSs, (b) some children (3.33%) at puberty (age range: 10-14 years), regardless of sex, might have a HPG > 10 mm, even though there was no pathology at the pituitary gland, and (c) to our knowledge, this retrospective MRI examination evaluated the relation of HPG with variant sella morphology in normal children for the first time in the literature.
分析小儿磁共振成像（MRI）图像上垂体高度（HPG）与鞍背高度（HDS）和鞍结节高度（HTS）之间的关系。
本研究纳入了180名年龄在1至18岁的健康儿童（100名男性和80名女性）的MRI切片。
HPG、HTS和HDS的平均测量值分别为6.66±1.58毫米、10.97±1.99毫米、13.62±2.67毫米。测量值在性别方面无统计学显著差异。所有参数均与小儿年龄相关。HPG在青春期前升高，青春期后下降（p<0.001）。HDS和HTS呈不规则升高（p<0.001）。有6名儿童（3.33%）的HPG>10毫米。没有儿童的HPG/HDS>1或HPG/HTS>1。
本研究在文献方面有三项重要补充：（a）所有小儿的HPG均明显小于HDS和HTS；（b）一些青春期（年龄范围：10至14岁）儿童（3.33%），无论性别，即使垂体无病变，HPG也可能>10毫米；（c）据我们所知，这项回顾性MRI检查首次在文献中评估了正常儿童中HPG与鞍形态变异之间的关系。
