CUDKOWICZ G, BENNETT M, SHEARER G M
Science. 1964 May 15;144(3620):866-8. doi: 10.1126/science.144.3620.866.
Bone marrow from normal and polycythemic mice was filtered through glasswool columns to remove cells other than "lymphocytes." For a given number of nucleated cells, filtered marrow was more efficient than the original marrow in repopulating the spleen of an isogenic recipient previously exposed to lethal irradiation. The proliferative capacity of both the filtered and unfiltered marrow suspensions appeared to be a constant function of the number of small and medium "lymphocytes" present and not of any other cell type.
将正常小鼠和红细胞增多症小鼠的骨髓通过玻璃棉柱进行过滤，以去除“淋巴细胞”以外的细胞。对于给定数量的有核细胞，过滤后的骨髓在重新填充先前接受致死性照射的同基因受体的脾脏方面比原始骨髓更有效。过滤后的和未过滤的骨髓悬液的增殖能力似乎是存在的中小“淋巴细胞”数量的恒定函数，而不是任何其他细胞类型的函数。
