Fackler J C, Berkowitz I D, Green W R
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, Md.
Am J Dis Child. 1992 Nov;146(11):1294-6. doi: 10.1001/archpedi.1992.02160230052014.
To determine whether conventional cardiopulmonary resuscitation causes retinal hemorrhages in piglets.
Nonrandomized observations.
Animal physiology laboratory.
Six 3.5- to 4.5-kg piglets.
Fifty minutes of conventional, closed chest cardiopulmonary resuscitation.
MEASUREMENTS/MAIN RESULTS: Intrathoracic venous pressure (right atrium) and intracranial venous pressure (sagittal sinus) were directly measured. At 5 minutes of cardiopulmonary resuscitation, the mean (+/- SEM) sagittal sinus pressure was 41 +/- 8 mm Hg and the mean right atrial pressure was 58 +/- 9 mm Hg. The pressures were sustained throughout the 50 minutes of cardiopulmonary resuscitation. At autopsy, there was no gross or microscopic evidence of retinal hemorrhages.
These results support the conclusion that cardiopulmonary resuscitation does not cause retinal hemorrhages.
确定传统心肺复苏是否会导致仔猪视网膜出血。
非随机观察。
动物生理学实验室。
6只体重3.5至4.5千克的仔猪。
进行50分钟的传统闭胸心肺复苏。
测量指标/主要结果：直接测量胸内静脉压（右心房）和颅内静脉压（矢状窦）。在心肺复苏5分钟时，矢状窦平均（±标准误）压力为41±8毫米汞柱，右心房平均压力为58±9毫米汞柱。在整个50分钟的心肺复苏过程中，这些压力持续存在。尸检时，未发现视网膜出血的大体或微观证据。
这些结果支持心肺复苏不会导致视网膜出血这一结论。
