Doll D C, McCagh M F, Welton W A
JAMA. 1977 Jul 18;238(3):236-7. doi: 10.1001/jama.1977.03280030044020.
We report a case of squamous cell carcinoma of the lung associated with the sudden appearance of seborrheic keratosis and acquired ichthyosis. We conclude that the sign of Leser-Trélat is a rare cutaneous manifestation of internal malignant disease.