Bayer A S, Theofilopoulos A N, Eisenberg R, Friedman S G, Guze L B
JAMA. 1977 Aug 1;238(5):408-10.
A thrombotic thrombocytopenic purpura (TTP)-like syndrome was the chief presenting feature in two patients with infective endocarditis. Clinical and laboratory aberrations of the syndrome were rapidly reversed by specific antimicrobial therapy. Hypocomplementemia and high levels of circulating immune complexes were detected initially in both patients. Because these returned to normal as the TTP syndrome abated, an immunopathologic mechanism may have been operative.
血栓性血小板减少性紫癜（TTP）样综合征是两名感染性心内膜炎患者的主要临床表现。该综合征的临床和实验室异常通过特异性抗菌治疗迅速得到逆转。两名患者最初均检测到低补体血症和高水平的循环免疫复合物。由于这些指标随着TTP综合征的缓解而恢复正常，免疫病理机制可能起了作用。
