MANLEY G
J Clin Pathol. 1964 May;17(3):220-4. doi: 10.1136/jcp.17.3.220.
Sections of the ascending aorta of 27 cases of dissecting aneurysm were compared histologically with the ascending aortae of 27 age- and sex-matched normotensive controls and 27 age- and sex-matched hypertensive controls. Elastic fragmentation and loss was seen to a similar degree in each series. Strip-like areas of muscle necrosis appeared to be associated as much with hypertension as with dissection. Two cases of dissecting aneurysm showed giant-cell aortitis. Mucopolysaccharide ;cysts' were seen more frequently, but by no means invariably, in the dissecting series. The only abnormality that distinguished the dissecting aortae from the normotensive and hypertensive controls with any constancy was an increase in the degree of metachromasia of the ground substance.
对27例夹层动脉瘤患者的升主动脉切片与27例年龄和性别匹配的血压正常对照者以及27例年龄和性别匹配的高血压对照者的升主动脉进行了组织学比较。在每个系列中均观察到弹性纤维断裂和缺失的程度相似。条状肌肉坏死区域似乎与高血压以及夹层形成都有很大关联。2例夹层动脉瘤显示巨细胞性主动脉炎。在夹层动脉瘤系列中，“粘多糖囊肿”更常见，但并非总是如此。唯一能始终将夹层动脉瘤的主动脉与血压正常和高血压对照者区分开的异常是基质异染性程度增加。
