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老年患者院外心脏骤停后的生存率。比利时脑复苏研究组。

Survival after out-of-hospital cardiac arrest in elderly patients. Belgian Cerebral Resuscitation Study Group.

作者信息

Van Hoeyweghen R J, Bossaert L L, Mullie A, Martens P, Delooz H H, Buylaert W A, Calle P A, Corne L

机构信息

University of Antwerp, Belgium.

出版信息

Ann Emerg Med. 1992 Oct;21(10):1179-84. doi: 10.1016/s0196-0644(05)81742-1.

Abstract

STUDY OBJECTIVES

To study whether age of the cardiac arrest patient is related to prognostic factors and survival.

STUDY DESIGN

Retrospective analysis of a prospective registration of cardiac arrest events in the mobile ICUs of seven participating hospitals.

STUDY POPULATION

Two thousand seven hundred seventy-six out-of-hospital cardiac arrests in which advanced life support was initiated. Cardiac arrests with a precipitating event requiring specific therapeutic consequences and with specific prognosis were not included in the analysis (eg, trauma, exsanguination, drowning, sudden infant death syndrome).

RESULTS

Neither resuscitation rate (23%) nor mortality caused by a neurologic reason (9%) was significantly different between age groups. Mortality after CPR of non-neurologic etiology was significantly higher in the elderly patient (younger than 40 years, 16%; 40 to 69 years, 19%; 70 to 79 years, 30%; 80 years or older, 34%; P less than .005) and had a negative effect on survival in resuscitated elderly patients (P less than .05). Elderly patients more frequently had a dependent lifestyle before the arrest (P less than .025), an arrest of cardiac origin (P less than .001), electromechanical dissociation as the type of cardiac arrest (P less than .025), and a shorter duration of advanced life support in unsuccessful resuscitation attempts (r = -.178, P less than .0001).

CONCLUSION

Because survival two weeks after CPR was not significantly different between age groups, we suggest that decision making in CPR should not be based on age but on factors with better predictive power for outcome and quality of survival.

摘要

研究目的

研究心脏骤停患者的年龄是否与预后因素及生存率相关。

研究设计

对七家参与医院的移动重症监护病房中前瞻性登记的心脏骤停事件进行回顾性分析。

研究对象

两千七百七十六例启动了高级生命支持的院外心脏骤停病例。分析不包括伴有需要特殊治疗后果和特定预后的诱发事件的心脏骤停(如创伤、失血、溺水、婴儿猝死综合征)。

结果

各年龄组之间的复苏率(23%)和神经源性死亡(9%)均无显著差异。非神经源性病因的心肺复苏术后死亡率在老年患者中显著更高(年龄小于40岁,16%;40至69岁,19%;70至79岁,30%;80岁及以上,34%;P<0.005),并且对复苏成功的老年患者的生存率有负面影响(P<0.05)。老年患者在心脏骤停前更常处于依赖性生活方式(P<0.025),心脏源性骤停(P<0.001),心脏骤停类型为电机械分离(P<0.025),以及在复苏未成功的尝试中高级生命支持的持续时间较短(r=-0.178,P<0.0001)。

结论

由于各年龄组心肺复苏术后两周的生存率无显著差异,我们建议心肺复苏的决策不应基于年龄,而应基于对预后和生存质量具有更好预测能力的因素。

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