Sebag C, Lavergne T, Ollitrault J, Cabanis C, Le Heuzey J Y, Slama M, Motté G, Guize L
Service de cardiologie, hôpital A.-Béclère, Clamart.
Arch Mal Coeur Vaiss. 1992 Jun;85(6):853-62.
Catheter ablation of the atrioventricular junction may be proposed for the treatment of certain atrial arrhythmias resistant to antiarrhythmic therapy. One of the methods currently being evaluated uses radio-frequency energy which has certain advantages compared with direct current ablation because of the progressive and limited lesions it produces. This technique was used in 24 patients with atrial arrhythmias resistant to antiarrhythmic therapy. The radio-frequency energy was delivered without general anaesthesia with HAT 100 and 200 (OSYPKA) generators in the unipolar mode (average 17.4 watts) for an average period of 22.3 +/- 8 seconds. The catheter (8F USCI suction catheter in the first 18 patients and a 7F Polaris Mansfield, deflectable catheter with a large distal electrode in the remainder) was positioned at the nodo-hisian junction at a point where the two distal electrodes recorded a large atrial deflection and the smallest possible hisian potential. The conduction defects induced during the acute phase generally remain stable in cases of complete atrioventricular block and tend to regress in cases of incomplete atrioventricular block despite initial control of atrioventricular conduction. During follow-up (21 +/- 16 months), 14 patients (58%) remained in complete atrioventricular block, 4 patients (17%) had controlled atrioventricular conduction with an acceptable ventricular rate with associated previously ineffective antiarrhythmic therapy. Radio-frequency ablation was a failure in 6 patients (25%). There were no haemodynamic, rhythmic or ischaemic complications during the acute phase or during follow-up. These results suggest radio-frequency energy is a seductive alternative to direct current ablation for percutaneous modification of atrioventricular conduction in patients with refractory atrial arrhythmias. However, simple modulation of atrioventricular conduction gives aleatory results due to the tendency to regression during follow-up. On the other hand, complete atrioventricular blocks created by radio-frequency energy are generally definitive and are associated with a junctional escape rhythm which is usually stable.
房室结导管消融术可用于治疗某些对抗心律失常治疗无效的房性心律失常。目前正在评估的一种方法是使用射频能量,与直流电消融相比,它具有一定优势,因为它产生的损伤是渐进性且有限的。该技术用于24例对抗心律失常治疗无效的房性心律失常患者。在未进行全身麻醉的情况下,使用HAT 100和200(OSYPKA)发生器以单极模式(平均17.4瓦)输送射频能量,平均持续时间为22.3±8秒。导管(前18例患者使用8F USCI吸引导管,其余患者使用7F北极星曼斯菲尔德可弯导管,其远端电极较大)置于结希氏交界区,此时两个远端电极记录到较大的心房偏转和尽可能小的希氏电位。在急性期诱发的传导缺陷在完全性房室传导阻滞的情况下通常保持稳定,而在不完全性房室传导阻滞的情况下,尽管最初控制了房室传导,但仍有消退的趋势。在随访期间(21±16个月),14例患者(58%)仍处于完全性房室传导阻滞,4例患者(17%)通过联合先前无效的抗心律失常治疗,使房室传导得到控制,心室率可接受。6例患者(25%)射频消融失败。急性期或随访期间均未出现血流动力学、节律或缺血性并发症。这些结果表明,对于难治性房性心律失常患者,射频能量是直流电消融用于经皮改变房室传导的一种诱人替代方法。然而,由于随访期间有消退的趋势,简单调节房室传导会产生随机结果。另一方面,由射频能量造成的完全性房室传导阻滞通常是永久性的,且伴有通常稳定的交界性逸搏心律。