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Characteristics of labeling of the cerebellar Purkinje neuron by L7 antiserum.

作者信息

Berrebi A S, Mugnaini E

机构信息

Laboratory of Neuromorphology, University of Connecticut, Storrs 06269-4154.

出版信息

J Chem Neuroanat. 1992 May-Jun;5(3):235-43. doi: 10.1016/0891-0618(92)90048-u.

DOI:10.1016/0891-0618(92)90048-u
PMID:1418751
Abstract

Previously, it has been shown by light microscopy that antiserum to the L7 protein labels cerebellar Purkinje neurons. Herein we show by light and electron microscopic immunocytochemistry that all cerebellar Purkinje cells express L7 and that the gene product is distributed to all neuronal compartments, including the nucleus. Possible functional roles for L7, based on its subcellular localization, are discussed. L7 is proposed as an excellent marker molecule for future studies of normal and aberrant cerebellar development.

摘要

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