van Lith-Bijl J T, Mahieu H F, Patel P, Zijlstra R J
Department of Otorhinolaryngology-Head and Neck Surgery, Free University Hospital, Amsterdam, The Netherlands.
Eur Arch Otorhinolaryngol. 1992;249(6):354-7. doi: 10.1007/BF00179389.
Since its introduction in 1980, the standard Groningen button prosthesis has been of proven value for post-laryngectomy voice rehabilitation. Its relatively high airflow resistance has, however, been the cause of failure in achieving good post-laryngectomy tracheoesophageal shunt speech in some patients. The low-resistance Groningen button (LRGB) was therefore designed, thus reducing airflow resistance by 50% when compared to the standard device. The clinical performance of the LRGB, and the effect of prophylactic amphotericin, was assessed in 32 patients. The device lifetime, intratracheal phonatory pressures and patients' subjective acceptances of the prosthesis were recorded. Present findings showed that the majority of the patients preferred the LRGB as it required less effort to operate than the standard device. The intra-tracheal phonatory pressure was found to increase with time, but this change was prevented with the prophylactic use of amphotericin to inhibit concurrent colonization by Candida spp, which also helped to prolong the prosthesis lifetime.
自1980年引入以来，标准的格罗宁根纽扣式假体已被证明对喉切除术后的语音康复具有价值。然而，其相对较高的气流阻力在一些患者中导致无法实现良好的喉切除术后气管食管瘘语音。因此设计了低阻力格罗宁根纽扣式假体（LRGB），与标准装置相比，气流阻力降低了50%。对32例患者评估了LRGB的临床表现及预防性使用两性霉素的效果。记录了装置使用寿命、气管内发声压力及患者对假体的主观接受度。目前的研究结果表明，大多数患者更喜欢LRGB，因为与标准装置相比，操作时所需的力气更小。发现气管内发声压力随时间增加，但预防性使用两性霉素抑制念珠菌属的同时定植可防止这种变化，这也有助于延长假体使用寿命。
