Karumo I, Rehunen S, Näveri H, Alho A
Ann Chir Gynaecol. 1977;66(3):164-9.
Clinical examination of the knee joint of 16 meniscectomy patients was performed and muscle biopsies were taken preoperatively and four weeks postoperatively from the vastus medialis of the quadriceps muscle. Corresponding investigations were performed in 15 healthy volunteer controls. One group of the meniscectomy patients was given routine postoperative physiotherapy, the other group intensive physiotherapy. Type I and II muscle fibres were determined from the muscle biopsies of the myosin-ATPase staining method. No difference was observed in the clinical and histochemical findings between the patients given routine and intensive physiotherapy respectively. Compared with the controls, the older patients had clinical quadriceps atrophy preoperatively, but there were no differences in the muscle fibre composition. After meniscectomy the patients developed even more marked quadriceps atrophy, which was more manifest in the patients with a good preoperative muscle status. The surface areas of the type I and II fibres of the operated patients diminished compared with the samples from the healthy volunteer controls. Only in the male patients was the decrease in the type I muscle area considerable. The present data indicate that meniscectomy is accompanied by a marked change in the clinical and histochemical appearance of the quadriceps muscle compared with the muscle status following meniscus injury; the extent of physiotherapy as carried out in the present study did not significantly modify the results.
对16例半月板切除术患者的膝关节进行了临床检查，并在术前及术后四周从股四头肌的股内侧肌取肌肉活检样本。对15名健康志愿者对照组进行了相应的检查。一组半月板切除术患者接受常规术后物理治疗，另一组接受强化物理治疗。通过肌球蛋白 - ATP酶染色法从肌肉活检样本中确定I型和II型肌纤维。分别接受常规和强化物理治疗的患者在临床和组织化学检查结果上未观察到差异。与对照组相比，年龄较大的患者术前存在股四头肌萎缩，但肌纤维组成没有差异。半月板切除术后，患者出现更明显的股四头肌萎缩，术前肌肉状态良好的患者更为明显。与健康志愿者对照组的样本相比，手术患者的I型和II型纤维表面积减小。仅男性患者的I型肌面积有显著下降。目前的数据表明，与半月板损伤后的肌肉状态相比，半月板切除术伴随着股四头肌临床和组织化学外观的显著变化；本研究中进行的物理治疗程度并未显著改变结果。
