Kreis T E
European Molecular Biology Laboratory, Heidelberg, Germany.
Curr Opin Cell Biol. 1992 Aug;4(4):609-15. doi: 10.1016/0955-0674(92)90079-r.
Transport of cargo through and from the Golgi complex is mediated by vesicular carriers and transient tubular connections. Two classes of vesicle have been implicated in the biosynthetic or anterograde membrane traffic of this organelle. Both classes of vesicle are coated on the cytoplasmic surface with proteins, of which at least one component is related. Tubular connections also enable exchange of material between membrane-bounded compartments associated with the Golgi complex, most obviously in cells that have been treated with the drug, brefeldin A. Coat proteins appear to be involved in the regulation of these transport processes. Their putative functions include sorting of cargo, as well as regulation of budding, fusion or targeting of the membrane carriers.
货物进出高尔基体复合体的运输是由囊泡载体和短暂的管状连接介导的。两类囊泡参与了该细胞器的生物合成或顺行性膜运输。这两类囊泡在细胞质表面都被蛋白质包裹，其中至少有一种成分是相关的。管状连接也使得与高尔基体复合体相关的膜结合区室之间能够进行物质交换，这在使用药物布雷菲德菌素A处理过的细胞中最为明显。包被蛋白似乎参与了这些运输过程的调节。它们假定的功能包括货物分选，以及对膜载体出芽、融合或靶向的调节。
