Moodaley L C, Woodward E G, Liu C S, Buckley R J
Contact Lens and Prostheses Department, Moorfields Eye Hospital, London.
Br J Ophthalmol. 1992 Oct;76(10):590-1. doi: 10.1136/bjo.76.10.590.
It is observed that few patients over the age of 60 regularly attend the keratoconus clinic at Moorfields Eye Hospital. The hypothesis that patients with keratoconus have a shorter life expectancy owing to underlying connective tissue related disease was tested. From patient records a sample of 337 keratoconus patients aged at least 40 years by 1991 were identified, of which 279 were living, 13 were deceased, and 45 were untraceable. The mortality rate for keratoconus patients was compared with that of the general population using actuarial English life tables. Results show no significant difference between the general population mortality rate and that of the keratoconus sample even with adjustment for social class. Possible explanations for the non-attendance of older patients are discussed.
据观察，很少有60岁以上的患者定期前往摩尔菲尔德眼科医院的圆锥角膜诊所。对圆锥角膜患者因潜在的结缔组织相关疾病而预期寿命较短这一假设进行了检验。从患者记录中，确定了截至1991年年龄至少为40岁的337名圆锥角膜患者样本，其中279人在世，13人已去世，45人无法追踪。使用精算英语寿命表将圆锥角膜患者的死亡率与普通人群的死亡率进行了比较。结果显示，即使对社会阶层进行了调整，普通人群死亡率与圆锥角膜样本死亡率之间也没有显著差异。讨论了老年患者不就诊的可能原因。
