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[烧伤患者的肠内营养]

[Enteral nutrition in burn patients].

作者信息

Pereira J L, Garrido M, Gómez-Cía T, Serrera J L, Franco A, Pumar A, Relimpio F, Astorga R, García-Luna P P

机构信息

Unidad de Nutrición Clínica y Dietética (Servicio de Endocrinología), Hospital Universitario Virgen del Rocío, Sevilla.

出版信息

Nutr Hosp. 1992 Sep-Oct;7(5):340-5.

PMID:1420487
Abstract

UNLABELLED

Nutritional support plays an important role in the treatment of patients with burns. Due to the severe hypercatabolism that develops in these patients, oral support is insufficient in most cases, and this makes it essential to initiate artificial nutritional support (either enteral or parenteral). Enteral nutrition is more physiological than parenteral, and data exist which show that in patients with burns, enteral nutrition exercises a protective effect on the intestine and may even reduce the hypermetabolic response in these patients. The purpose of the study was to evaluate the effectiveness and tolerance of enteral nutritional support with a hypercaloric, hyperproteic diet with a high content of branched amino acids in the nutritional support of patients suffering from burns.

MATERIAL

The study included 12 patients (8 males and 4 females), admitted to the Burns Unit. Average age was 35 +/- 17 years (range: 21-85 years). The percentage of body surface affected by the burns was 10% in two cases, between 10-30% in three cases, between 30-50% in five cases and over 50% in two cases. Initiation of the enteral nutrition was between twenty-four hours and seven days after the burn. The patients were kept in the unit until they were discharged, and the average time spent in the unit was 31.5 days (range: 17-63 days). Total energetic requirements were calculated based on Harris-Benedict, with a variable aggression factor depending on the body surface burned, which varied from 2,000 and 4,000 cal day. Nitrogenous balance was determined on a daily basis, and plasmatic levels of total proteins, albumin and prealbumin on a weekly basis.

RESULTS

There was a significant difference between the prealbumin values at the initiation and finalization of the enteral nutrition (9.6 +/- 2.24 mg/dl compared with 19.75 +/- 5.48 mg/dl; p < 0.001). The nitrogenous balance improved, changing from -5.4 in the second week to positive values by the fourth and fifth weeks of treatment. Tolerance to the enteral diet was very good, and only mild complications such as diarrhoea developed in two patients.

CONCLUSIONS

Enteral nutrition is a suitable nutritional support method for patients with burns, which maintains the nitrogenous balance positive and improves the visceral protein parameters in these patients at an early stage, with very few complications.

摘要

未标注

营养支持在烧伤患者的治疗中起着重要作用。由于这些患者会出现严重的高分解代谢,大多数情况下口服营养支持不足,因此启动人工营养支持(肠内或肠外)至关重要。肠内营养比肠外营养更符合生理需求,并且有数据表明,对于烧伤患者,肠内营养对肠道具有保护作用,甚至可能降低这些患者的高代谢反应。本研究的目的是评估在烧伤患者的营养支持中,采用高热量、高蛋白且富含支链氨基酸的饮食进行肠内营养支持的有效性和耐受性。

材料

该研究纳入了12名入住烧伤科的患者(8名男性和4名女性)。平均年龄为35±17岁(范围:21 - 85岁)。烧伤累及的体表面积,2例为10%,3例在10% - 30%之间,5例在30% - 50%之间,2例超过50%。肠内营养在烧伤后24小时至7天内开始。患者在科室一直住院至出院,在科室的平均住院时间为31.5天(范围:17 - 63天)。根据哈里斯 - 本尼迪克特公式计算总能量需求,并根据烧伤的体表面积调整应激系数,每天的能量需求在2000至4000千卡之间。每天测定氮平衡,每周测定血浆总蛋白、白蛋白和前白蛋白水平。

结果

肠内营养开始时和结束时的前白蛋白值存在显著差异(分别为9.6±2.24毫克/分升和19.75±5.48毫克/分升;p < 0.001)。氮平衡得到改善,从第二周的 - 5.4变为治疗第四周和第五周的正值。对肠内饮食的耐受性非常好,仅2例患者出现腹泻等轻度并发症。

结论

肠内营养是烧伤患者合适的营养支持方法,可使氮平衡保持正值,并在早期改善这些患者的内脏蛋白参数,且并发症极少。

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