Hansbrough J F
Department of Surgery, University of California, San Diego Medical Center, San Diego, California 92103, USA.
Gastrointest Endosc Clin N Am. 1998 Jul;8(3):645-67.
Early and continued nutritional support has been determined to be an important component of therapy for seriously burned patients. The hypermetabolic response to severe injury requires increased calorie and protein intake to blunt the catabolism and loss of lean muscle mass. Enteral feeding has been found to directly nourish the gastrointestinal tract and may help reverse the defective gut barrier which accompanies burn shock. In contrast, intravenous nutritional support appears to lack effectiveness in burn patients and may actually increase morbidity and mortality.
早期持续的营养支持已被确定为严重烧伤患者治疗的重要组成部分。对严重损伤的高代谢反应需要增加热量和蛋白质摄入,以抑制分解代谢和瘦肌肉质量的损失。已发现肠内喂养可直接滋养胃肠道,并可能有助于逆转烧伤休克伴随的肠道屏障缺陷。相比之下,静脉营养支持在烧伤患者中似乎缺乏效果,实际上可能会增加发病率和死亡率。