Bartlett J G, Belitsos P C, Sears C L
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
Clin Infect Dis. 1992 Oct;15(4):726-35. doi: 10.1093/clind/15.4.726.
Chronic diarrhea is one of the hallmarks of advanced human immunodeficiency virus (HIV) disease. The symptoms of this complication are troublesome, have a significant impact on the patient's quality of life, and in severe cases can lead to extreme abnormalities in fluids and electrolytes and can even cause death. The workup for AIDS-associated diarrhea is often frustrating and frequently unrewarding. However, during the last 10 years, much has been learned about the causes of diarrhea; while treatment is still often ineffective, some advances have been made. Dr. John G. Bartlett and his colleagues in the Department of Medicine at Johns Hopkins University School of Medicine have been responsible for many of these advances. In this AIDS Commentary, these experts discuss recent advances that have enhanced our understanding of chronic diarrhea in HIV-infected persons and offer their recommendations for the most efficient and effective approach to managing these patients.
慢性腹泻是晚期人类免疫缺陷病毒（HIV）疾病的标志之一。这种并发症的症状令人困扰，对患者的生活质量有重大影响，严重时可导致体液和电解质极度异常，甚至会导致死亡。对艾滋病相关腹泻的检查往往令人沮丧，且常常没有结果。然而，在过去十年中，我们对腹泻的病因有了很多了解；虽然治疗往往仍然无效，但也取得了一些进展。约翰·霍普金斯大学医学院医学系的约翰·G·巴特利特博士及其同事促成了其中的许多进展。在这篇艾滋病评论中，这些专家讨论了最近的进展，这些进展加深了我们对HIV感染者慢性腹泻的理解，并就管理这些患者的最有效方法提出了建议。
