Nagle J F
Department of Biological Science, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213.
Biophys J. 1992 Aug;63(2):366-70. doi: 10.1016/S0006-3495(92)81602-8.
Long tail kinetics describe a variety of data from complex, disordered materials that cannot be described by conventional kinetics. It is suggested that the kinetics of diffusive motion in complex biological media, such as cytoplasm or biomembranes, might also have long tails. The effects of long tail kinetics are investigated for two standard biophysical measurements, fluorescence recovery after photobleaching (FRAP), and dynamic light scattering (DLS). It is shown that long tail kinetic data would yield significantly distorted and misleading results when analyzed assuming conventional kinetics.
长尾动力学描述了来自复杂、无序材料的各种数据，这些数据无法用传统动力学来描述。有人提出，在复杂的生物介质（如细胞质或生物膜）中，扩散运动的动力学也可能具有长尾特性。针对两种标准的生物物理测量方法——光漂白后荧光恢复（FRAP）和动态光散射（DLS），研究了长尾动力学的影响。结果表明，当假设为传统动力学进行分析时，长尾动力学数据会产生明显扭曲且具有误导性的结果。
