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鼠疫耶尔森菌和大肠杆菌共有的噬菌体

BACTERIOPHAGE COMMON TO PASTEURELLA PESTIS AND ESCHERICHIA COLI.

作者信息

HERTMAN I

出版信息

J Bacteriol. 1964 Oct;88(4):1002-5. doi: 10.1128/jb.88.4.1002-1005.1964.

DOI:10.1128/jb.88.4.1002-1005.1964
PMID:14219010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC314845/
Abstract

Hertman, I. (Israel Institute for Biological Research, Ness Ziona, Israel). Bacteriophage common to Pasteurella pestis and Escherichia coli. J. Bacteriol. 88:1002-1005. 1964.-Phage Y of Pasteurella pestis and phage T(3) of Escherichia coli are serologically related and have common bacterial hosts. Anti-Y serum neutralizes the homologous phage and phage T(3) to a similar extent. Anti-Y serum, absorbed with T(3), still neutralizes the activity of phage Y for P. pestis, but not the activity for E. coli B/r. A mutant of phage Y was isolated from turbid plaques formed on P. pestis at 27 C. This mutant infected P. pestis only if this organism had been grown at 27 C; it lost its infectivity towards E. coli B/r and was not neutralized by anti-T(3) serum. From this phage, additional mutants were isolated on P. pestis, some of which were infective for both P. pestis and E. coli B/r and some of which remained infective for P. pestis only. The reacquired infectivity for E. coli B/r was neutralized by anti-T(3) serum. The name T(3)P is suggested for phage Y.

摘要

赫特曼,I.(以色列内斯锡安生物研究所)。鼠疫耶尔森菌和大肠杆菌共有的噬菌体。《细菌学杂志》88:1002 - 1005。1964年。——鼠疫耶尔森菌的噬菌体Y和大肠杆菌的噬菌体T(3)在血清学上相关且有共同的细菌宿主。抗Y血清对同源噬菌体和噬菌体T(3)的中和程度相似。用T(3)吸收后的抗Y血清仍能中和噬菌体Y对鼠疫耶尔森菌的活性,但不能中和其对大肠杆菌B/r的活性。从27℃下在鼠疫耶尔森菌上形成的浑浊噬菌斑中分离出噬菌体Y的一个突变体。该突变体只有在鼠疫耶尔森菌于27℃下生长时才能感染它;它对大肠杆菌B/r失去了感染性,且不被抗T(3)血清中和。从这个噬菌体中,在鼠疫耶尔森菌上又分离出了其他突变体,其中一些对鼠疫耶尔森菌和大肠杆菌B/r都有感染性,而一些仅对鼠疫耶尔森菌仍有感染性。重新获得的对大肠杆菌B/r的感染性被抗T(3)血清中和。建议将噬菌体Y命名为T(3)P。

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本文引用的文献

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